Gynaecologic Oncology

The Department of Gynecologic Oncology was established in July 2013 and is located at the Puxi Campus of Renji Hospital. It currently has 36 official beds and 25 medical and nursing staff members at all levels; there are 8 physicians, including 5 with doctoral degrees, 3 pursuing doctoral degrees, and 3 with senior professional titles; and 17 nurses. The department mainly treats patients with benign and malignant gynecologic tumors for whom surgery is the primary treatment, while also providing comprehensive tumor treatment such as chemotherapy and immunotherapy and targeted therapy. The Department of Gynecologic Oncology primarily admits patients undergoing surgery for gynecologic malignancies. Its disease spectrum includes common and rare gynecologic malignancies such as cervical cancer, endometrial cancer, ovarian cancer, and vulvar cancer. Comprehensive treatment centered on surgery is provided in accordance with authoritative international and domestic guidelines and standards. Surgery for gynecologic malignancies is the department’s distinctive diagnostic and treatment service. Since its establishment, the department has completed nearly 10,000 high-risk and highly complex grade IV open/laparoscopic gynecologic oncology surgeries, with grade IV surgeries accounting for more than 50% annually. It routinely performs new technologies and procedures, including “3D laparoscopic radical surgery for cervical cancer without a uterine manipulator,” “laparoscopic fertility-sparing surgery for cervical cancer,” “laparoscopic nerve-sparing surgery for cervical cancer,” and “fluorescence-guided sentinel lymph node biopsy with comprehensive staging surgery for endometrial cancer.” To date, more than 200 fertility-sparing surgeries for cervical cancer have been completed, with a low recurrence rate and satisfactory pregnancy rate. With the support of the hospital’s multidisciplinary collaboration platform, the department has developed a distinctive surgical approach to open cytoreductive surgery for advanced ovarian cancer; the rate of satisfactory cytoreductive surgery exceeds 80%, improving patient prognosis. The department also performs surgery for benign gynecologic tumors. More than 80% of benign tumor surgeries are completed laparoscopically. Single-port laparoscopy and da Vinci robotic laparoscopic surgery are performed, and various procedures are routinely carried out, including laparoscopic surgery for ovarian cysts, uterine fibroids, endometriosis, and uterine prolapse. For surgery for deep endometriosis (urinary tract DIE, intestinal DIE, pelvic floor DIE, etc.), satisfactory treatment outcomes have been achieved through multidisciplinary collaboration. The department has also accumulated extensive clinical experience in managing difficult and critically ill patients with multiple comorbidities, advanced age, and other characteristics. In addition to surgical treatment, the department closely follows international and domestic treatment standards. Alongside conventional chemotherapy, it actively develops new treatment modalities such as immunotherapy and targeted therapy. In recent years, molecular genetic testing for gynecologic malignancies has been routinely performed to standardize malignant tumor treatment strategies. For patients with recurrent advanced disease, the department explores effective treatment approaches and has undertaken or participated in 6 GCP drug studies. The Department of Gynecologic Oncology continuously promotes comprehensive disciplinary development and actively conducts scientific research and talent training. The department’s research focuses are clinical and basic research on gynecologic malignancies, research on the pathogenesis of deep infiltrating endometriosis, and research on the clinical application of artificial intelligence in gynecologic malignancies. Over the past 5 years, the department has undertaken 1 National Natural Science Foundation of China project and 8 provincial- and ministerial-level projects; led 13 clinical and GCP studies; participated in 2 international cooperation projects; published more than 80 papers; served as editor-in-chief or deputy editor-in-chief of 3 monographs; contributed to 7 textbooks and monographs; and served as editor-in-chief or deputy editor-in-chief of 8 relevant discipline guidelines.