Ultrasound

The Department of Ultrasound of Shanghai Pulmonary Hospital was established in the 1980s. After the efforts of several generations, it has now developed into a comprehensive department integrating ultrasound diagnosis and treatment, electrocardiographic diagnostic care, medical education, and scientific research, and has become one of the hospital’s developing disciplines. It is a training unit for master’s and doctoral graduate students of Tongji University.

I. Discipline Scale

At present, the department has a total of 28 medical technology, nursing, and clerical staff members, including 13 physicians: 1 chief physician, 3 associate chief physicians, and 8 attending physicians. One person has a doctoral degree, 5 have master’s degrees, 1 is currently pursuing a doctoral degree, and 2 are currently pursuing master’s degrees. A total of 3 people have obtained teaching titles, including 1 associate professor and doctoral supervisor and 2 lecturers.

Department members hold positions in multiple academic organizations, including 20 national-level positions and 24 provincial- and municipal-level positions, as detailed in Table 1. There are 7 positions at the level of deputy chairperson or above, as follows:

Deputy Chairperson, Ultrasound Special Committee, Tuberculosis Branch, Chinese Medical Association

Member of the Tuberculosis Prevention and Control Branch of the Chinese Medical Promotion Association and Deputy Leader of the Ultrasound Group

Deputy Chairperson, Critical Care Ultrasound Special Committee, Ultrasound Branch, Asia-Pacific Primary Health Care Association

Member of the Ultrasound Medicine Specialty Branch of the Shanghai Medical Association and Deputy Leader of the Interventional Group

Council Member of the Shanghai Society of Ultrasound in Medicine and Engineering and Deputy Chairperson of the Interventional Special Committee

Standing Committee Member of the Ultrasound Medicine Special Committee of the Shanghai Association of Integrated Traditional Chinese and Western Medicine and Deputy Leader of the Cardiopulmonary Ultrasound Group

Deputy Chairperson of the Thoracic Intervention Group, Ultrasound Intervention Special Committee, Interventional Physicians Branch, Chinese Medical Doctor Association

Table 1 Academic Positions Held

Position

National-Level Academic Organizations

Provincial- and Ministerial-Level Academic Organizations

Deputy Chairperson

4

1

Standing Committee Member

4

/

Standing Council Member

/

2

Council Member

/

1

Secretary

/

2

Committee Member

10

16

Deputy Leader of a Group

2

2

Total

20

24

The Department of Ultrasound currently has 10 ultrasound examination rooms and 1 electrocardiogram examination room. The main work area is located on the second floor of Building No. 2. In addition, 2 ultrasound examination rooms have been opened in the basement of Building No. 3, achieving “one-door closure” for tuberculosis. The department provides abdominal, cardiac, vascular, superficial organ, and gynecological ultrasound examinations, as well as interventional ultrasound diagnosis and treatment services. It has also gradually improved its specialty clinics, establishing expert, general, interventional ultrasound specialty-disease, lower-extremity thrombosis screening, integrated tumor imaging, and lung tumor imaging-pathology MDT clinics, greatly facilitating patients’ access to medical care.

II. Professional Characteristics

On the basis of routine ultrasound and electrocardiography services, and relying on the hospital’s specialty in pulmonary diseases, the department has carried out a series of new technologies and projects, including

1. Ultrasound-guided needle biopsy of the lung, lymph nodes, liver, superficial masses, and other sites; ultrasound-guided puncture drainage of refractory pleural and abdominal effusions; and applications of new ultrasound technologies, such as contrast-enhanced ultrasound, elastography, image-fusion volume navigation, and speckle tracking, in the diagnosis and treatment of pulmonary diseases, comprehensively enhancing the department’s clinical capabilities.

2. Application of bedside ultrasound in respiratory critical care, with technologies including lung ultrasound, cardiac color Doppler ultrasound, and vascular color Doppler ultrasound comprehensively applied to the assessment of cardiac, pulmonary, and circulatory function in critically ill patients.

3. In cooperation with the hospital’s lung transplantation clinical team, the department has carried out transesophageal echocardiography and perioperative ultrasound assessment for lung transplantation and ECMO, providing real-time visualized monitoring for multiple important clinical management processes.

With the continuous optimization of the department’s examination and diagnostic processes, work efficiency has continuously improved and the volume of services has steadily increased. The workload and implementation of new technologies from 2013 to 2022 are shown in Figure 1 and Table 2.

Figure 1 Medical Service Volume of the Department of Ultrasound (2013-2022)

Table 2 Implementation of New Technologies in the Department of Ultrasound (2017-2022)

III. Continuing Education

The department has successively organized 4 continuing education courses, which received an extremely positive response and enhanced the discipline’s influence:

2018 Shanghai Municipal Continuing Education Program “Training Course on New Advances in Ultrasound Diagnosis and Treatment of Pulmonary Diseases”

2019 National Continuing Education Program “The Second Training Course on New Advances in Ultrasound Diagnosis and Treatment of Pulmonary Diseases and Ultrasound New Technology Forum.”

2021 National Continuing Education Program “The Third Training Course on New Advances in Ultrasound Diagnosis and Treatment of Pulmonary Diseases and Ultrasound New Technology Forum”

2022 National Continuing Education Course “The Fourth Training Course on New Advances in Ultrasound Diagnosis and Treatment of Pulmonary Diseases and Ultrasound New Technology Forum”

The department has held multiple academic salons with distinctive characteristics, such as the “Ultrasound and Scientific Research” series of online salons, the “Interventional Ultrasound Salon,” the “Young Clinical Researcher Salon,” and more than 30 sessions of the “Lung Special Topic” online course. Their excellent content and distinctive characteristics have attracted extensive attention from the industry.

The department is a training unit for master’s and doctoral graduate students of Tongji University. Director Wang Yin serves as a master’s and doctoral supervisor. At present, the department has enrolled 1 master’s student and 2 doctoral students, and participates in the training of 3 master’s students. It has provided instruction to a total of 19 advanced-study students and 14 standardized resident trainees. The department has a strong atmosphere for teaching and scientific research; teaching and learning complement each other, enabling students to gain and acquire knowledge.

IV. Scientific Research Projects and Published Papers

The department has conducted in-depth clinical and basic research on pulmonary ultrasound, obtaining multiple National Natural Science Foundation of China and provincial- and ministerial-level scientific research projects. It has published a total of 45 scientific research papers, including 25 SCI research articles, with a highest IF of 29.146. This original research article, published in 2021 in the TOP imaging journal Radiology, was independently completed by the department team led by Director Wang Yin in its entirety, from design and implementation to data analysis and writing, and is an important milestone in the improvement of the scientific research level of the Department of Ultrasound of our hospital. The department has also served as chief editor of 1 monograph, deputy chief editor of 1 monograph, and contributing editor of 1 monograph, and has obtained 7 utility model and invention patents.

Table 3 Scientific Research Projects Obtained (2018-2022)

Person in Charge

Category

Start and End

Time

Title

Wang Yin

General Program of the National Natural Science Foundation of China

2023/01-2026/12

Study on Clarifying the “Window Period” of Vascular Normalization Based on an Intelligent Quantitative System for Contrast-Enhanced Ultrasound Blood Perfusion to Improve the Efficacy of Immune Checkpoint Inhibitors in Lung Cancer

Wang Yin

2022 Medical Innovation Research Special Project of the Shanghai Municipal Commission of Science and Technology

2022/07-2025/06

Study on Regulating the Process of Vascular Normalization Based on a Quantitative System for Contrast-Enhanced Ultrasound Blood Perfusion to Improve the Efficacy of Immune Checkpoint Inhibitors in Lung Cancer

Wang Yin

2018 Guidance Project of the Shanghai Municipal Commission of Science and Technology

2018/10-2021/09

Application of Conventional Ultrasound Combined with Contrast-Enhanced Ultrasound Technology in the Diagnosis of Pulmonary Tuberculosis

Wang Yin

2019 Technical Standards Project of the Shanghai Municipal Commission of Science and Technology

2019/09-2022/08

Technical Standards and Application Research of Artificial Intelligence-Assisted Ultrasound Diagnosis of Subpleural Pulmonary Lesions

Wang Yin

Clinical Research Fund of Shanghai Pulmonary Hospital

2019/12-2021/11

Development and Application Research of an Artificial Intelligence Neural Network System for Ultrasound Image Segmentation and Diagnosis of Subpleural Pulmonary Lesions

Wang Yin

Clinical Research Fund of Shanghai Pulmonary Hospital

2020/09-2023/08

The Value of Ultrasound-Guided Percutaneous Lung Needle Biopsy in the Diagnosis of Subpleural Pulmonary Lesions: A Prospective, Multicenter Cohort Study

Cong Yang

Open Project Fund of Shanghai Key Laboratory

2020/06-2022/12

Clinical Technical System for the Diagnosis of Pulmonary Mycosis by Ultrasound-Guided Needle Biopsy

Table 4 Representative Scientific Research Papers (First/Corresponding Author)

Authors

Journal

IF

Title

1.Bi K#, Zhou RR#, Zhang Y, Shen MJ, Chen HW, Cong Y, Zhu HM, Tang CH, Yuan J, Wang Y*

Radiology. 2021 , 301(1):200-210.

29.149

US Contrast Agent Arrival Time Difference Ratio for Benign versus Malignant Subpleural Pulmonary Lesions.

2.Meiqi Chang#, Zeyu Wang#, Caihong Dong#, Ruirui Zhou, Liang Chen, Hui Huang, Wei Feng, Ziliang Wang,* Yin Wang* and Yu Chen*

Advanced materials,

2023,2208817

32.086

Ultrasound-Amplified Enzyodynamic Tumor Therapy by Perovskite Nanoenzyme-Enabled Cell Pyroptosis and Cascade Catalysis.

3.Wang Y#, Bi K#, Shu J#, Liu X, Xu J, Deng G*

Nanoscale, 2019, 11(10): 4210-4218

6.97

Ultrasound-controlled DOX-SiO2 nanocomposites enhance the antitumour efficacy and attenuate the toxicity of doxorubicin

4.Ke Bi#, Demeng Xia#, Lin Fan#, Xiao-Fei Ye, Yi Zhang, Meng-Jun Shen, Hong-Wei Chen, Yang Cong, Hui-Ming Zhu, Chun-Hong Tang, Jing Yuan, Yin Wang*

Front Oncol, 2021 ,11:656060.

6.244

,Development and Validation of an Ultrasound Prediction Model for the Differential Diagnosis of Benign and Malignant Subpleural Pulmonary Lesions: A Large Ambispective Cohort Study.

5.Zhifang Li # , Chunmei Wang # , Chen Dai # , Ruizhi Hu , Li Ding, Wei Feng , Hui Huang , Yin Wang*, Jianwen Bai *, Yu Chen b*

Biomaterials, 287 (2022) 121668

15.304

Engineering dual catalytic nanomedicine for autophagy-augmented and ferroptosis-involved cancer nanotherapy.

6.Demeng Xia#, Gaoqi Chen#, Kaiwen Wu#, Mengxin Yu#, Zhentao Zhang, Yixian Lu, Lisha Xu* and Yin Wang*

Frontiers in Public, 2022-0695233-2

6.461

Research progress and hotspot of the Artificial Intelligence Application in the Ultrasound during 2011-2021: a bibliometric analysis .

7.Zhang C#, Xu L#, Deng G#, Ding Y, Bi K, Jin H, Shu J, Yang J, Deng H, Wang Z*, Wang Y*

Science China-Life Sciences, 2020, 63(8): 1265-1268 .

6.038

Exosomal HOTAIR promotes proliferation, migration and invasion of lung cancer by sponging miR-203

8.J Chen#, M Shen#, S Hou, X Duan, Y Cao. W Qin, Q Li, Y Zhang* and Y Wang*.

Biomedical Signal Processing and Cnontrol.

5.076

Automated Interpretation of Four Lung Ultrasonographic Features with Spit Attention and Mish Function based Resne

9.Xu Y#, Zhang Y#, Bi K#, Ning Z, Xu L, Shen M,Deng G*, Wang Y* (Corresponding author, IF:)

,J Digit Imaging. 2020,33(5):1155-1166.

4.903

Boundary Restored Network for Subpleural Pulmonary Lesion Segmentation on Ultrasound Images at Local and Global Scales.

10.Bi K#, Wang B#, Zhang Y, Shen MJ, Chen HW, Zhu HM, Tang CH, Wang Y*

Ultrasound Med Biol. 2021 ,47(5):1261-1268.

3.694

Contrast-Enhanced Ultrasound of the Pleural Cavity: A Method to Locate Pleural Catheters and Identify Fibrous Septa.

11. Li W#, Shen M#, Zhang Y, Cong Y, Zu H, Chen H, Wang Y*

Ultrasound Med Biol. 2021,47(5):1212-1218

3.694

A Model for Predicting Malignant Sub-pleural Solid Masses Using Grayscale Ultrasound and Ultrasound Elastography.

V. Discipline Development and Talent Cultivation

The department attaches importance to discipline development and talent cultivation. At present, 1 physician is pursuing a doctoral degree and 2 are pursuing master’s degrees. Multiple physicians have gone to hospitals inside and outside the city for further study and exchanges. At present, 4 physicians have completed the three-stage training in tumor ablation therapy and obtained ablation therapy certificates; 10 physicians have undergone training in transesophageal echocardiography.

Department members actively participate in conference submissions, difficult-case discussions, and professional and science-popularization competitions. They have delivered more than 300 conference presentations, submitted 156 papers, and presented more than 100 posters, receiving 25 awards for excellent papers, excellent posters, and various competitions. Department members

For many years, the department has been committed to creating a fair, impartial, united, and mutually supportive departmental culture, and has actively carried out free medical consultation activities to give back to society.

Table 5 Awards Received in Academic Activities (2018-2022)

Award Recipient

Honor

Shen Mengjun

Third Prize in the “Shanghai Young Physicians’ Ultrasound Case Competition” at the 2020 Shanghai Ultrasound Annual Conference, “Paper Excellence Award” at the 2020 Shanghai Ultrasound Medicine New Technology Forum, Second Prize in the “Needle Biopsy Case Competition” at the 2020 National Symposium on Standardized Clinical Application of Interventional Ultrasound, “Excellent Paper” at the 2021 Annual Conference of Interventional Physicians of the Chinese Medical Doctor Association, Excellent Paper at the 14th Asian Federation of Societies for Ultrasound in Medicine and Biology Joint Conference and the 21st National Academic Conference on Ultrasound Medicine of the Chinese Medical Association, Excellent Paper at the 22nd National Academic Conference on Ultrasound Medicine of the Chinese Medical Association, and Second Prize in the “FUTURE US” Competition at the 2022 First Maritime Ultrasound Physicians Forum

Zhang Yi

Third Prize in the 2018 Shanghai Young Physicians’ Skills Competition, Second Prize in the “Needle Biopsy Case Competition” at the 2020 National Symposium on Standardized Clinical Application of Interventional Ultrasound

Bi Ke

“Excellence Award” in the Young and Middle-Aged Presentation Competition at the 2018 Academic Conference Commemorating the 60th Anniversary of the Founding of Chinese Ultrasound Diagnosis, “Excellence Award” in the E-poster Competition at the 2018 Academic Conference Commemorating the 60th Anniversary of the Founding of Chinese Ultrasound Diagnosis

Shu Jixin

Excellent Paper at the 2020 Chinese Ultrasound Physicians Conference

Chen Hongwei

Third Prize in the Ultrasound Technologist Skills Competition of the “Ultrasound Craftsman Cup” at the 2022 Annual Conference of the Ultrasound Physicians Branch of the Shanghai Medical Doctor Association

Ma Qian

“Excellence Award” in the Ultrasound Technologist Skills Competition of the “Ultrasound Craftsman Cup” at the 2022 Annual Conference of the Ultrasound Physicians Branch of the Shanghai Medical Doctor Association

Table 6 Provincial-, Ministerial-Level, and In-Hospital Awards (2018-2022)

Award Recipient

Honor

Department of Ultrasound Collective

2022 Shanghai Health Industry Youth May Fourth Medal—Collective Model Award

Department of Ultrasound Collective

2022 Shanghai Pulmonary Hospital Medical Technology Comprehensive Party Branch Excellent Organizational Life Case Award

Wang Yin

First and Second Prizes in the New Technologies and New Projects of Shanghai Pulmonary Hospital for 2017, 2018, and 2019, Third Prize in the Clinical Achievements of Shanghai Pulmonary Hospital for 2020, and Outstanding Department Director of Shanghai Pulmonary Hospital for 2017, 2018, 2020, and 2021

Shu Jixin

Third Prize in the 9th Shanghai Science Popularization Explanation Competition, Excellent Science Popularization Ambassador of Yangpu District in the 9th Shanghai Science Popularization Explanation Competition, Advanced Individual in Striving for Excellence in the 2021-2022 Yangpu District Whole-Population Science Popularization Competition, and one of the “Top 10 Works” in the First Short-Video Competition of Shanghai Pulmonary Hospital

Shen Mengjun

Second Prize in the 2019 New Technologies and New Projects of Shanghai Pulmonary Hospital, and one of the “Top 10 Works” in the First Short-Video Competition of Shanghai Pulmonary Hospital

Zhang Yi et al.

Outstanding Employees of Shanghai Pulmonary Hospital: Zhang Yi, Tang Chunhong, Shen Mengjun, Chen Hongwei, Ma Qian, Cong Yang, Yuan Jing, Hong Meijun

Zhang Lei et al.

“Top 10 Window Stars” of Shanghai Pulmonary Hospital: Luo Benfang, Zhang Lei, Luo Yuanming

Chen Hongwei et al.

Outstanding Party Members of Shanghai Pulmonary Hospital: Shen Mengjun, Chen Hongwei, Zhang Yi